The 4 Most Popular Weight Loss Drugs In 2021

The 4 Most Popular Weight Loss Drugs In 2021

The 4 Most Popular Weight Loss Drugs In 2021: What You Need To Know About GLP-1’s

GLP-1 agonists have grown quickly in popularity amongst weight loss patients. You may know them commonly as Wegovy, Saxenda or Ozempic; among others. Why have these drugs proven successful patients? Here’s how they work:

  1. GLP -1 stands for “Glucagon-like Peptide 1”, and when naturally produced, it belongs to a family of hormones produced in the gut.
  2. It acts by:
    • Releasing insulin in response to food.
    • Decreasing glucagon, keeping your blood sugar in balance.
    • Increasing satiety, which allows you to feel full.
    • Decreasing gastric motility, slowing food traveling through the digestive tract.
    • Protecting pancreatic B cells which produce insulin
    • Protects heart function by supporting myocardial electric and mechanical performance
    • Increasing moment of glucose to muscle cells.
    • Decreases the body’s ability to transform non-carbohydrates into glucose
    • Increases cardiac output
  3. Synthetically made, these medications have a similar effect on the body. They may be taken orally or by self-administered injection. Some of the most commonly prescribed are:
    • Trulicity (Dulaglutide)—once a week by injection
    • Ozempic (Semaglutide)—once a week by injection
    • Wegovy (Semaglutide) – once a week by injection
    • Saxenda (Liraglutide) – daily by injection
    • Rybelsus (Semaglutide) – taken by mouth once daily
  4. Side effects and contraindications to be aware of:
    • Weakness, Dizziness, Headache
    • Nausea, Vomiting, Diarrhea, or Constipation
    • Local injection site reaction
    • Hypoglycemia
    • Not indicated for those with MEN syndrome or medullary carcinoma of thyroid.

Think you may be a candidate for these medications? We’re currently accepting new patients for our weight loss program, and would love to help you reach your goals! Contact us at 317-548-4666 or

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