At MD Wellness Center & Med Spa, we use Platelet-Rich Fibrin (PRF) — the next generation of PRP (Platelet-Rich Plasma) — to help your skin renew itself naturally. While both treatments use your own blood to harness growth factors and stimulate collagen, PRF delivers a higher concentration of platelets and stem cells, resulting in smoother texture, improved tone, and long-lasting rejuvenation.
All aesthetic injection treatments are performed exclusively by our MD to ensure precision, safety, and consistency in your results.
What It Is
Platelet-Rich Fibrin (PRF) is an advanced regenerative treatment that uses your own blood to create a serum rich in platelets, stem cells, and growth factors — key components that trigger collagen and elastin production for firmer, smoother skin.
How It Works
A small sample of blood is drawn and spun at a low speed to create a golden fibrin matrix packed with platelets and stem cells. This concentrated serum is then applied or injected into targeted areas of the face — such as the under-eyes, cheeks, or around fine lines — where it stimulates new collagen, improves texture, and enhances elasticity over time.
PRF vs. PRP
Both treatments harness your platelets for skin rejuvenation, but PRF is processed more gently, preserving more white blood cells and stem cells. This allows for slower release and longer-lasting results, giving you a more youthful, natural glow.
Your PRF session begins with a quick blood draw, followed by gentle preparation of the platelet-rich fibrin serum. Depending on your treatment plan, PRF may be injected into fine lines or under-eye areas or combined with microneedling to boost collagen production across the face.
Treatment Time: 45–60 minutes
Downtime: Minimal — mild redness for 24–48 hours
Results: A natural glow within days; continued collagen renewal for 4–6 weeks
Series: Most patients benefit from 3 sessions, spaced 4–6 weeks apart
This treatment can also be combined with RF Microneedling or dermal fillers for enhanced volume and tightening.
We recommend starting with a free aesthetic consultation to evaluate your skin tone, discuss your goals, and determine if PRF is the right fit for you.
Serving Indianapolis, Carmel, Fishers, and surrounding areas
Call 317-548-4666 or click below to schedule your consultation at MD Wellness Center & Med Spa today.
At MD Wellness Center & Med Spa, PRF and PRP treatments are performed by experienced aesthetic professionals under the supervision of Dr. Srinivasu Kesa, MD, a licensed physician with more than 30 years of medical experience and advanced training in aesthetic injectables, lasers, and regenerative skin therapies.
Our team’s focus is on delivering natural, healthy-looking results — using your body’s own regenerative power to restore confidence in your skin.
Physician-supervised regenerative care
Safe, all-natural collagen stimulation
Personalized protocols for your skin’s needs
Combination therapies for next-level rejuvenation
Both PRP (Platelet-Rich Plasma) and PRF (Platelet-Rich Fibrin) harness your body’s natural healing power to restore and rejuvenate the skin. The key difference is that PRF is processed at a lower centrifuge speed, allowing it to retain more white blood cells, stem cells, and a fibrin matrix that slowly releases growth factors over time. This leads to longer-lasting and more natural results compared to PRP.
Our team is here to help you make an appointment with the specialists that you need: call us or fill the online booking form
6822 E 82nd Street #310, Indianapolis IN 46250
*Disclaimer: The information on this website is provided for general informational and educational purposes only and is not intended as medical advice. Content on this site is not a substitute for professional diagnosis, treatment, or medical decision-making.
*Photos and testimonials are for illustrative purposes only. Individual results vary.